Nikel-catalizad oliminiative couption yo guhuza alnogashira ya alkylpyridinipuum umunyu wa add yashoboje nn2 pincer ligand

Alkynes arahari cyane mubicuruzwa karemano, molelogisi ikora molekile nibikoresho byimikorere. Muri icyo gihe, ni ngombwa kandi hagati muri synthesis kama kandi barashobora kunyuramo imiti myinshi. Kubwibyo, iterambere ryuburyo bworoshye kandi bwiza bwa alkynes byihutirwa cyane kandi birakenewe. Nubwo sonogashira reaction ya Catalies yinzibacyuho nimwe muburyo bwiza kandi bworoshye bwo guhagarika ARKYNES, reacling reaction irimo alkynes iterwa na alkyl electrophile iterwa nukuntu bh. Biracyafite ibibazo nubushakashatsi buke, cyane cyane bigarukira gusa ku bidukikije kandi bihenze alKene. Kubwibyo, ubushakashatsi niterambere rya Sonogashira reactions nshya, bidahendutse kandi byoroshye kuboneka amoko agaragara bizagira akamaro gakomeye haba muri synthesis na synthesis hamwe nibikorwa byinganda. Ikipe Yateguwe neza kandi itezimbere itandukaniro, yoroshye kandi ihamye ya NN2 Pincer Ligand itoroshye kandi ya mbere itobora alkynic hamwe ninkomoko nini ya Nikel, ihendutse kubona. Umusaraba wambukiranya wakoreshejwe neza gukwirakwiza no guhinduranya ibicuruzwa bisanzwe nibiyobyabwenge, bigaragaza uburyo bwiza bwo kugahuza hamwe na synthesi, kandi bitanga ishusho ya synthesi ya alkyl-yasimbuwe alkyl-yasimbuwe. N'uburyo bufatika.